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University of Washington

Rosetta@home needs your help to determine the 3-dimensional shapes of proteins in research that may ultimately lead to finding cures for some major human diseases. By running the Rosetta program on your computer while you don't need it you will help us speed up and extend our research in ways we couldn't possibly attempt without your help. You will also be helping our efforts at designing new proteins to fight diseases such as HIV, Malaria, Cancer, and Alzheimer's. Please join us in our efforts! Rosetta@home is not for profit.

We believe that we are getting closer to accurately predicting and designing protein structures and protein complexes, one of the holy grails of computational biology. But in order to prove this, we require an enormous amount of computing resources, an amount greater than the world's largest super computers. This is only achievable through a collective effort from volunteers like you.


Page Icon Comprehensive computational design of ordered peptide macrocycles

Page Icon Evolution of a designed protein assembly encapsulating its own RNA genome

Page Icon Massively parallel de novo protein design for targeted therapeutics

Page Icon The coming of age of de novo protein design


Project Statistics

Project Total Credit Project Compute Speed (GFlops)
76171287761 145164
Project Avg Daily Credit (7 Day) Project Avg Daily Credit (40 Day)
25512900 30962200
W.A.S (Work Availability Score) Z.C.D (Zero Credit Days)
0.82 1
Last Stats Update
2019-02-14 21:13:52

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Project News Feed

Congrats to the collaborative WeFold group for their recent paper published in Nature Scientific Reports. Thank you to all R@h volunteers who contributed to this work.

Tue, 03 Jul 2018 00:13:42 GMT

Congrats to the WeFold group for their recent publication, An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12, in Nature Scientific Reports. As CASP13 is currently in full swing, this article describes the results and analysis of the CASP11 and CASP12 WeFold coopetition (cooperation and competition) . Most of the models used by WeFold for CASP12 (and currently for CASP13) were generated by Rosetta@home volunteers. Congrats and Thank you!

Rosetta Android version 4.10 released

Fri, 27 Apr 2018 23:29:47 GMT

This version uses a relatively recent version of the Rosetta source. It includes updates to the cyclic peptide folding protocol among other code updates and additions since the previous build. Please post comments and issues in this thread.